Endocrine Abstracts

We present this 62-year-old man with a background of Marfan’s Syndrome, aortic valve replacement, atrial fibrillation and asthma who presented with increasingly severe episodic hypoglycaemia over a period of 22 years. Of note he was not diabetic and was not on any hypoglycaemia-inducing medications. Extensive investigations included the following: 72 hr fast, 5 hr OGTT, continuous glucose monitoring, basic biochemistry, hormone profiles (GH, LH...

We present this 62-year-old man with a background of Marfan’s Syndrome, aortic valve replacement, atrial fibrillation and asthma who presented with increasingly severe episodic hypoglycaemia over a period of 22 years. Of note he was not diabetic and was not on any hypoglycaemia-inducing medications. Extensive investigations included the following: 72 hr fast, 5 hr OGTT, continuous glucose monitoring, basic biochemistry, hormone profiles (GH, LH...

Section: Case history: 73-year old gentleman referred from GP with a two month history of worsening dizziness, malaise, postural hypotension and general deterioration and spiking pyrexia ranging 38-40°C over 3 weeks. PMH of NSCLC T2b N0- left lower lobectomy & chemotherapy 3 years prior.Section: Investigations and treatment: At re-presentation his CT TAP showed bilateral bulky adrenal glands but no other abnormality. The patient’s bloods sh...

Background: Acute adrenal insufficiency is a life threatening condition. Signs and symptoms are often non-specific. The adrenal gland has the richest arterial supply of any tissue with limited venous drainage and this mismatch predisposes to haemorrhagic infarction. We present a case report of acute adrenal insufficiency due to bilateral adrenal haemorrhagic infarcts associated with an open ankle fracture.Case history: A 52-year man fell from a ladder su...

A 52 year old lady was admitted with collapse in May 2001 with h/o being nauseous, generally unwell, off her feet and food for several weeks. GP consultation five weeks before, for similar complaints, resulted in thyroid function tests confirming hypothyroidism. Thyroxine 25 mcg was commenced by the GP and uptitrated to 50 mcg. She however deteriorated despite this treatment becoming increasingly lethargic and sleepy. On admission she appeared tanned, BP was 93/50 she was dysa...

Introduction: Vitamin D deficiency is common in ethnic minority population living in UK. It is a relatively easily treatable condition. However, if left untreated it may lead to chronic secondary hyperparathyroidism and onto tertiary hyperparathyroidism. We report three cases of severe vitamin D deficiency who presented with hypercalcaemia.CasesWe report three patients. 60 and 46 years old ladies, both of south-asian origin, a 46 y...

Background: The short synacthen test (SST) is the most commonly performed investigation to assess for suspected adrenocortical dysfunction. We investigated how random cortisol levels may relate to pass/fail on the STT.Methods: We analysed the relation between random cortisol measurements taken between 04.40 and 20.52 in the day and results of SST baseline and 30/60 min cortisol performed over a 12 month period (338 SSTs) at Salford Royal Hospital. Serum ...